Minoxidil works as a vasodilator, enhancing blood flow and nutrient supply to the hair follicles. It reduces the length of the resting (telogen) phase, encouraging follicles to transition more quickly into the growth (anagen) phase, and extends the duration of that growth phase.1
Dutasteride blocks both type I and type II forms of the enzyme 5-alpha-reductase, leading to a more substantial reduction in dihydrotestosterone (DHT) levels compared to finasteride, which only targets type II. DHT is a key factor in androgenetic alopecia, which can also affect women and leads to gradual shrinkage of hair follicles. By lowering DHT levels, dutasteride helps to minimize further follicle miniaturization, supporting the maintenance of existing hair and potentially encouraging new growth.2
Biotin, also known as vitamin B7, is essential for healthy hair growth, particularly in individuals who are deficient in this nutrient. Biotin deficiency may lead to hair thinning and hair loss. Supplementing with biotin supports the production of keratin, the structural protein that forms hair, skin, and nails. In people with biotin deficiency, supplementation may help strengthen the hair shaft.3