AquaBiome

Some of the potential benefits include but are not limited to:

• Addresses inflammation^2,3
• Supports skin repair function, regeneration, and overall skin health^1-3
• Promote collagen production^1,2
• Encourage formation of new blood vessels^2,3
• Promote skin firmness, elasticity, and resilience^1,2
• Help minimize the appearance of fine lines and support skin texture¹
• Provide deep hydration and moisture retention¹
• Contribute to the appearance of smooth, radiant complexion^1,2

This medication needs to be stored in the refrigerator. Consult with a healthcare provider if pregnant or planning to become pregnant.

Pregnant or Nursing Women

While GHK-Cu is generally suitable for topical use, consult a healthcare professional before use during pregnancy or breastfeeding.

Individuals with Sensitive Skin

If you have highly sensitive skin, introduce the product gradually by using it every other night, or consult with a dermatologist for personalized advice.

People with Allergies to Copper Peptides

Those with known sensitivities or allergies to copper peptides should avoid using this product.

GHK-Cu is an endogenous occurring copper-binding tripeptide composed of glycine (G), histidine (H), and lysine (K). It has a high affinity for copper ions (Cu²⁺), forming a stable and biologically active complex that may support copper’s bioavailability and intracellular activity.^2,3 This interaction is associated with several biological processes involved in maintaining skin health, collagen support, healthy hair, immune function, and angiogenesis (the formation of new blood vessels)^1-3. Additionally, GHK-Cu is formulated to help address oxidative stress and support the skin's response to environmental factors.^2,3

Q: Is GHK-Cu Cream suitable for all skin types?

A: Yes, GHK-Cu is generally well tolerated, even with those with sensitive skin. However, people with very reactive or compromised skin should start with a patch test.

Q: Will this cream stain the skin blue?

A: No, not in the cream form. While it is blue in color, our well-formulated cream does not stain. If the color is strong, it usually fades quickly upon absorption.

Q: When will I see possible outcomes?

A: Outcomes will vary between patients. Some may notice changes in skin texture and hydration within 1–2 weeks, but collagen remodeling and deeper changes may take 4–12 weeks with consistent use.

Q: If GHK-Cu contains copper should I be worried about copper toxicity?

A: GHK-Cu uses a very small amount of copper, keeps it tightly bound in a peptide complex that inactivates its harmful free‑radical chemistry, and operates within the body’s normal copper‑handling pathways, so when used as directed it is not expected to meaningfully raise systemic copper levels in people with normal copper metabolism.

IMPORTANT INFORMATION ABOUT COMPOUNDED MEDICATIONS

This medication has been compounded (custom-prepared) by a pharmacy. Compounded medications are specially prepared for individual patient needs based on a valid prescription and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. These statements have not been evaluated by the FDA.

This compounded preparation:

• Has not been approved by the FDA
• Has not undergone FDA review for safety, effectiveness, or quality
• Is prepared specifically for you based on your prescriber's order
• Individual outcomes may vary

Dosing is determined by the prescribing provider based on patient-specific factors. Always follow your healthcare provider's instructions. Compounded medications are not subject to FDA approval and lack the same safety and efficacy data as FDA-approved commercial medications. This medication should be prescribed and monitored by a licensed healthcare professional familiar with the condition being addressed and the specific applications of the medication.

1. Dou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. Aging Pathobiol Ther. 2020 Mar 27;2(1):58-61. doi:
10.31491/apt.2020.03.014. PMID: 35083444; PMCID: PMC8789089

2. Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7. PMID: 26236730; PMCID: PMC4508379.

3. Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987. PMID: 29986520; PMCID: PMC6073405.

This medication has been compounded (custom-prepared) by a pharmacy.
This compounded preparation:

• Has not been approved by the FDA
• Has not undergone FDA review for safety, effectiveness, or quality
• Is prepared specifically for you based on your prescriber's order
• Individual outcomes may vary

Disclaimer:

Compounded medications are specially prepared for individual patient needs based on a valid prescription and, as such, are not reviewed or approved by the U.S. Food and Drug Administration (FDA) for safety or efficacy. These statements have not been evaluated by the FDA.

This information is for educational and informational purposes only. It is not medical advice or a health, diagnosis, or a treatment recommendation. Always consult your healthcare provider before starting any new medication to determine whether it is appropriate for your individual circumstances. Contact your healthcare provider with any questions regarding a medical condition.